Cell Dissociation Market 2024 – Market Size & Segments Analysis, Industry Trends, Manufacturers Analysis, Opportunities and Forecast 2034

Cells dissociation is a process of breaking down the inter-cellular connections between cells of cell culture or tissue samples, through which individual cells or cells surrounding the extracellular matrix can be easily dissociated. This can be achieved either via enzymatic or non-enzymatic approach, depending on the experiment/application. Enzymatic dissociation is based on the use of proteolytic enzymes such as trypsin, collagenase, or Dnase, among others. These enzymes cut the proteins which hold the cells together and thus leading to cells detachment. Non-enzymatic dissociation techniques encompass the use of EDTA chelating agents or mechanical disruption means including scraping or agitation among others. Tissue dissociation is the mechanism for cell dissociation as well as cell detachment, and it is also used in other applications.

The separation of the cells from a natural environment makes it possible for scientists to observe the behavior and features of these cells outside their natural habitat in culture to increase the possibilities and applications of science. In the last few years, the global cell dissociation market has been growing rapidly and this is mainly due to the expansion in the number of laboratories working with cell based assays for drug development and discovery, the increase in chronic diseases load, and the growth of biopharmaceutical industry. The escalating incidence of chronic diseases such as cancer, cardiovascular diseases and neurodegenerative disorders has significantly ameliorated cell-based therapies, which in turn have boosted the market for cell dissociation products.

The cell dissociation market is anticipated to reach USD XXX.X million by 2034 from USD XXX.X million in 2023, at a CAGR of XX.X% during the forecast period.

Technological innovations including the invention of new enzymes and reagents for faster and better dissociation of cells are harnessing the dynamics to grow the market as cell separation techniques advance and cell viability is maintained. Similarly, the increasing application spectrum of cell biology research, specifically in areas such as stem cell research, tissue engineering, and regenerative medicine, is believed to also drive cell dissociation market growth during the forecast period 2024-2034.

Growth Drivers:

The increasing number of patients with chronic and age-related diseases results in stem cells which have made regenerative therapies widespread. Separation of cells is one of the important processes in the field of stem cells isolation and culture for tissue engineering and regenerative medicine. As regenerative therapies are new, this will undoubtedly lead to the increase in need for accurate and effective cell dissociation processes.

The area of tissue engineering and organoids culture creates new doors for cell dissociation products. Researchers are working on advanced methods for bioengineering of multi-tissue constructs and organoids for disease modeling, drug testing as well as organ replacement therapies. The dissociation of cells results in isolation of the cells within the engineered constructs and thus gives rise to the need for the developed reagents and methodologies.

The advent of personalized medicine and targeted therapies necessitates the application of advanced cell culture techniques, including cell dissociation in precision oncology, regenerative medicine, and immunotherapy research. The possibility of isolating and culturing of patient-derived cells has enabled researchers to create individualized treatments, as well as the improved clinical outcomes, which together with the demand for dissociation cell products have been made.

The popularity of cell-based assays and high-throughput screening technologies in drug discovery and toxicity testing drives the increase in demand for cell dissociation reagents. The validity and reliability of such assays is highly dependent on the good quality of dissociated cells. Pharmaceutical industry tends to demand quick and cost-effective drug discovery procedures. Accordingly, the need for cell dissociation technologies is expected to increase.

Cell Dissociation Segmentation:

By Product:

·         Enzymatic Dissociation Reagents

o   Trypsin

o   Collagenase

o   Hyaluronidase

o   DNase

o   Papain

o   Elastase

o   Other Enzymes

·         Non-Enzymatic Dissociation Reagents

o   Mechanical

o   Chemical

·         Instruments & Accessories

By Tissue Type:

·         Epithelial Tissue

·         Connective Tissue

·         Others

By Application:

·         Tissue Dissociation

·         Cell Detachment

·         Others

By End-User:

·         Pharmaceutical & Biotechnology Companies

·         Research & Academic Institutes

·         Others

By Region:

·         North America

·         Europe

·         Asia Pacific

·         Latin America

·         Middle East and Africa

Cell Dissociation Market by Product Review:

Based on the product, the cell dissociation market is segmented into three segments including enzymatic dissociation reagents, non-enzymatic dissociation reagents, and instruments & accessories. On the basis of product, the enzymatic dissociation reagents segment is expected to dominate the market in terms of market share, while the non-ferrous metals segment is predicted to grow at the highest rate in terms of CAGR during the forecast period.

Cell Dissociation Market by Tissue Type Review:

Based on the tissue type, the market is segmented into epithelial tissue, connective tissue, and others. On the basis of tissue type, the connective tissue segment is expected to be the largest in terms of market share, while the epithelial tissue segment is predicted to grow at the highest rate in terms of CAGR during the forecast period.

Cell Dissociation Market by Application Review:

Based on the application, the market is segmented into tissue dissociation, cell detachment, and others. On the basis of application, the tissue dissociation segment is expected to be the largest in terms of market share, while the cell detachment segment is predicted to grow at the highest rate in terms of CAGR during the forecast period.

Cell Dissociation Market by End-User Review:

Based on the end-user, the market is segmented into pharmaceutical & biotechnology companies, research & academic institutes, and others. On the basis of end-user, the pharmaceutical & biotechnology companies segment is expected to be the largest in terms of market share, while the research & academic institutes segment is predicted to grow at the highest rate in terms of CAGR during the forecast period.

Regional Outlook:

The cell dissociation market research report offers detailed analysis and forecasts for five major regions i.e., North America, Europe, Asia Pacific (APAC), Latin America, and the Middle East & Africa.

The North America region is forecasted to dominate the global cell dissociation market followed by Asia Pacific, Europe, Latin America, and Middle East & Africa during the forecast period 2023-2030.

North America will retain its dominant place in the global cell dissociation market with a projected market share of XX.X% in 2023. The regional cell dissociation market is mainly stimulated by effective healthcare system, big R&D investments, and acceptance of biotechnological tools. The region enjoys outstanding biopharmaceutical companies, academic institutions and beneficial reimbursement plans. Moreover, safety and quality of products are controlled by strict rules hence development of the market. The United States is the leading supplier, with Canada coming in second. Some notable trends with cell dissociation in the region going forward include enhancement of personalized medicine and cell-based therapies which contribute greatly to market growth and innovation, this is predicted to further propel the cell dissociation market in the region during the period 2024-2034.

The North American region, which holds a significant share of the total cell dissociation market globally, is majorly led by the USA and Canada. The size of the local market is buoyed by the driving factors that include the presence of reputable pharmaceutical and biotechnology companies, top-class research centers, and high incidence of chronic diseases that require advanced cell-based therapies.

Due to an ever-increasing number of chronic diseases like cancer, diabetes, and cardiovascular disorders in North America, there is a rise in the need for cutting-edge therapeutics and treatment techniques. For instance, according to the CDC data, in 2022, this number was closer to 60 percent for adult Americans with at least one chronic condition. Cell therapies, which frequently involve cell dissociation methods, have demonstrated huge potential in treatment of those unmet medical needs and giving patients better healthcare outcomes.

Moreover, government funding agencies within the region set aside a substantial amount of the budget to fund the basic and translational research in life sciences which is expected to fuel the market expansion in the region during the forecast period 2024-2034.

Asia Pacific is experiencing rapid growth of the cell dissociation market due to the augmentation of biopharmaceutical and healthcare industry, increased R&D investment, and budding consciousness of cell based therapies. Nations like China, India, and Japan are taking the lead in expanding the market with the help of government programs to boost life sciences R&D and attract foreign investments. However, surging cell-based therapies application, and growing partnerships between academic and research institutes, industry, and regions sales of the products in the Asia Pacific regions is likely to spur market growth during the forecast period of 2024 to 2034.

Key Companies in Cell Dissociation Market:

The research report offers a competitive analysis of prominent companies operating in the cell dissociation market. Some of the leading players profiled in the market research report include:

·         Thermo Fisher Scientific, Inc.

·         Merck KGaA

·         Cytiva

·         Becton, Dickinson and Company

·         Corning Incorporated

·         STEMCELL Technologies

·         PromoCell GmbH

·         Miltenyi Biotec

·         ATCC

·         HiMedia Laboratories

·         PAN-Biotech

·         AMSBIO

·         Neuromics

·         Other Players