Microcarriers Market 2024 – Market Size & Segments Analysis, Industry Trends, Manufacturers Analysis, Opportunities and Forecast 2030

Introduction:

The micocrarrier is a support matrix inside a bioreactor, which can provide anchoring site allowing cells to spread onto the matrix surface. Alternatively, cells are cultured on orthopodic surface of the spherical microcarriers so that each ball carries few hundred cells, and therefore expansion capacity can be multiplied several time over. The device makes it easy to develop and scale up culture systems when producing cell or protein-based therapies for industrial purposes or to be used in the laboratory. 

Microcarriers measure between 100 and 300 microns in diameter and can survive stirring. Sheets of cells grown as monolayers have a larger surface area to volume ratio, which makes cell production and expansion cost efficient. These microcarriers market have the primary role of facilitating the growth of the cells under controlled conditions. They are highly relevant in situations where traditional suspension cultures may be inappropriate, such as with adherent cell types. 

The microcarriers play an important role in the realm of cell culture technology being a crucial part of the system in the manufacture of biopharmaceutical and cellular products with high scalability and efficiency. The recent rise in the biopharmaceutical industry as a result of the need for more personalized medicines has seen a rapid adoption of microcarriers of cell culture processes. The trend of making continuous investments in R&D activities by pharmaceutical and biotechnology companies, focusing on the development of advanced microcarriers has contributed to market growth.

The microcarriers market is anticipated to reach USD XXX.X million by 2030 from USD XXX.X million in 2022, at a CAGR of XX.X% during the forecast period.

The trend towards single-use bioreactors, which is driven by their cost benefits and lower risk of contamination, has contributed significantly to the uptake of microcarrier. In addition to the aforementioned factors, the increasing popularity of the biopharmaceuticals industry, especially in the developing economies and innovation in the bioprocessing technologies, which includes the development of new microcarrier materials and improved scalability, is projected to contribute positively to the microcarriers market with an emerging forecast period of 2023-2030.

Growth Drivers:

In terms of key drivers, the jaw-dropping expansion in the biopharmaceutical industry can be considered as the first major impetus for the international market of microcarriers. It is widely accepted that the demand for effective cell culture technologies is due to the increased need to satisfy the requirements of individualized medicines, monoclonal antibodies, and cell-based therapies. They are, therefore, a central element in these processes, and as biopharmaceutical revolution continues to reform the healthcare paradigm, the demand for microcarriers will only skyrocket.

The steady investment by pharmaceutical and biotechnology companies in the research and development activities helps to foster the movement of such market. The search for new technologies and innovative solutions to cell culture processes has resulted in developing advanced and functional microcarriers. The emphasis on developing microcarriers with variable properties makes it possible to adapt them according to the needs of cell cultures and takes away the market’s competitive advantage.

In addition, the increasing demand for single use bioreactors in the biopharmaceutical industry is a key factor contributing to the rapid growth of microcarriers market. Susceptibility to contamination and a weak control of the production process creates high demand for the microcarriers that can be used in the single-use systems, which offer cost-effectiveness, reduced contamination risk, and increased flexibility in production processes. For the single-use bioreactors, microcarriers are manufactured in a way that provides scalability so that manufacturers can easily increase production to meet demand.

The development of microcarrier cell therapy applications is a new, profitable direction in the development of the market. However, due to the growing influence of cell therapy in the regenerative medicine sector, the demand for scalable and cost-effective cell culture technologies, including advanced microcarriers, becomes more important than ever before. The joining into cell therapy of microcarriers is aligned with the rapidly emerging opportunity of the market in regenerative medicine, which provides substantial opportunities of new revenue streams.

Microcarriers Segmentation:

By Product Type:

·         Consumables

o   Media

§  Serum-Based Media

§  Serum-Free Media

§  Other Media

o   Microcarrier Beads

§  Collagen-Coated Beads

§  Protein-Coated Beads

§  Cationic Beads

§  Untreated Beads

§  Other Microcarrier Beads

o   Reagents

o   Other Consumables

·         Equipment

o   Bioreactors

o   Single-Use Bioreactors

o   Stainless-Steel Bioreactors

o   Filtration & Separation Equipment

o   Cell Counters

o   Culture Vessels

o   Other Equipment

By Application:

·         Biopharmaceutical Production

o   Vaccine Production

o   Therapeutic Protien Production

o   Tissue Engineering & Regenerative Medicine, By Therapy Type

§  Cell & Gene Therapy

§  Other Tissue Engineering & Regenerative Medicine Applications

o   Tissue Engineering & Regenerative Medicine, By Cell Type

§  Stem Cells

·         Induced Pluripotent Stem Cells (iPSCs)

·         Hematopoietic Stem Cells (HSCs)

·         Mesenchymal Stem Cells

§  Immune Cells

·         NK Cells

·         T-Cells

·         Other Immune Cells

§  Other Cell Types

·         Other Applications

By End-User:

·         Contract Research Organizations (CROs) & Contract Manufacturing Organizations (CMOs)

·         Pharmaceutical & Biotechnology Companies

·         Cell Banks

·         Academic & Research Institutes

By Region:

·         North America

·         Europe

·         Asia Pacific

·         Latin America

·         Middle East and Africa

 

Microcarriers Market by Product Type Review:

Based on the product type, the microcarriers market is segmented into three segments including the consumables, which is further sub-segmented into media, microcarrier beads, reagents, and other consumables, and equipment, which is further sub-segmented into bioreactors, cell counters, and cell vessels among others. On the basis of product type, the consumables segment is expected to dominate the market in terms of market share, while the segment is also predicted to grow at the highest rate in terms of CAGR during the forecast period.

Microcarriers Market by Application Review:

Based on the application, the microcarriers market is segmented into biopharmaceutical production, which is further sub-segmented into vaccine production, therapeutic protein production, and tissue engineering & regenerative medicine, and other applications. On the basis of application, the biopharmaceutical production segment is expected to be the largest in terms of market share, while the segment is also forecasted to grow at the highest rate in terms of CAGR during the forecast period.

Microcarriers Market by End-User Review:

Based on the end-user, the market is segmented into contract research organizations (CROs) & contract manufacturing organizations (CMOs), pharmaceutical & biotechnology companies, cell banks, and academic & research institutes. On the basis of end-user, the pharmaceutical & biotechnology companies segment is expected to be the largest in terms of market share, while the CROs & CMOs segment is predicted to grow at the highest rate in terms of CAGR during the forecast period.

Regional Outlook:

The microcarriers market research report offers detailed analysis and forecasts for five major regions i.e., North America, Europe, Asia Pacific (APAC), Latin America, and the Middle East & Africa.

The North America region is forecasted to dominate the global microcarriers market followed by Asia Pacific, Europe, Latin America, and Middle East & Africa during the forecast period 2023-2030.

In the global microcarriers market, the North America region is projected to hold a dominant market share of XX.X% in the year 2022. The regional microcarriers market is largely because of a stunning biopharmaceutical industry, high research and development capabilities, and an impressive market demand for novel cell culture technologies. However, the growing usage of single-use bioreactors in North America has a favorable impact on microcarrier demand. This combination of the bioreactor and the microcarriers gives them an element of flexibility and the economy of cell culture procedures. Next, the increasing adoption of personalized medicine increases the need for accurate cell culture techniques, contributing to the Asia-Pacific microcarriers market, which is expected to grow further in the forecast period 2023-2030.

North America, including the United States and Canada, is a significant biotechnology market, acting as a base point for both research, development, and commercialization. In North America, the microcarriers market is the most significant in the world due to the presence of leading pharmaceutical and biotechnology companies, research institutions, and a favorable regulatory environment.

Some of the emerging trends in North America include the desire for customized microcarrier solutions. Chemical companies are creating microcarriers designed for a particular cell type and application, in order to meet the requirements of the biopharmaceutical sector. This trend represents the area’s dedication to accuracy and efficient cellular growth.

Microcarrier design advancements are also under continuous research in North America. The area is also projected to grow in the context of technological trends such as surface modifications, coatings and material science innovations that facilitate the availability of microcarriers with tunable properties.

It is considered that Asia Pacific is the fastest growing market for microcarriers, with the CAGR of X.X% being the highest. Microcarrier reagents in the Asia-Pacific market, which is dominated by the increasing biopharmaceutical and production capacity, are in high demand. China, India, and other countries are embracing a role as influential contenders in the competitive international arena, providing cost-effective solutions that greatly contribute to the total market revenue. In terms of the growth of the market in the region, factors like the hike in investments into the biopharmaceutical sector, the growing emphasis on healthcare infrastructure development, and even the increasing number of the population all contribute to the market growth in the region. The continued development of bioprocessing technologies, accompanied by larger-scale production using microcarriers, is anticipated to continue the growth of the market in the region over the forecast period 2023-2030.

Key Companies in Microcarriers Market:

The research report offers a competitive analysis of prominent companies operating in the Microcarriers market. Some of the leading players profiled in the market research report include:

·         Thermo Fisher Scientific Inc.

·         Sartorius AG

·         Merck KGaA

·         Corning Incorporated 

·         Eppendorf SE

·         Lonza

·         Getinge AB

·         ChemoMetec

·         FUJIFILM Corporation

·         Esco Lifesciences Group Ltd.

·         Entegris

·         Other Players